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Protein Ontology report - smad2 isoform unphosphorylated 1 (human)
PR:000025960 - http://purl.obolibrary.org/obo/PR_000025960
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:000025960   
  PRO namesmad2 isoform unphosphorylated 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hSMAD2/iso:[Long/Short]/UnPhos:1
  Definition"A mothers against decapentaplegic homolog 2 (human) that lacks phosphorylation on the last two Ser of the C-terminal SSxS motif." [PMID:19135894, PRO:CNA, PRO:DAN] 
  PRO Categoryorganism-modification 
  ParentPR:Q15796 mothers against decapentaplegic homolog 2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?
organism-modification



PR:000025960 smad2 isoform unphosphorylated 1 (human)

hSMAD2/iso:[Long/Short]/UnPhos:1


organism-modification



PR:000045371 smad2 isoform Long unphosphorylated 1 (human)

hSMAD2/iso:Long/UnPhos:1


organism-modification



PR:000045494 smad2 isoform Short unphosphorylated 1 (human)

hSMAD2/iso:Short/UnPhos:1


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hSMAD2/iso:[Long/Short]/UnPhos:1 forms found in complexes   

hSMAD2/iso:[Long/Short]/UnPhos:1 Component
Complexes
PR:000045371 hSMAD2/iso:Long/UnPhos:1 PR:000025952 smad2-smad4-ski protein complex 2 (human)
PR:000025965 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000045371 hSMAD2/iso:Long/UnPhos:1
UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291
acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:8752209
enablesGO:0005515 protein binding PMID:8980228
located_inGO:0005737 cytoplasm PMID:15280432; PMID:17074053
GO:0005769 early endosome PMID:12356868