PRO_ID Object_term Object_syny Modifier Relation Ontology_ID Ontology_term Relative_to Interaction_with Evidence_source Evidence_code Taxon Inferred_from DB_ID Date Assigned_by Comment PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 enables GO:0005160 transforming growth factor beta receptor binding PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 enables GO:0042803 protein homodimerization activity PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 located_in GO:0005615 extracellular space PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 increased enables GO:0008083 growth factor activity PR:000000616 PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA