PRO_ID Object_term Object_syny Modifier Relation Ontology_ID Ontology_term Relative_to Interaction_with Evidence_source Evidence_code Taxon Inferred_from DB_ID Date Assigned_by Comment PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) enables GO:0004713 protein tyrosine kinase activity Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA Target=PR:000037447 (TIRAP protein in this complex). PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) located_in GO:0005886 plasma membrane Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA