[Term] id: PR:000000002 name: E3 ubiquitin ligase SFC complex Skp1 subunit def: "A protein that has a core domain composition consisting of an N-terminal Skp1 family, tetramerisation domain (Pfam:PF03931) followed by a Skp1 family, dimerisation domain (Pfam:PF01466). Skp1 proteins bind several F-box-containing proteins, and are involved in the ubiquitin protein degradation pathway." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF028729 is_a: PR:000000001 ! protein