[Term]
id: PR:000000027
name: smad protein
def: "A protein with core domain composition consisting of one MH1 domain (Pfam:PF03165) at the N terminus and one MH2 domain (Pfam:PF03166) at the C-terminus, separated by a non-conserved linker region. Smad proteins are mediators of signal transduction in transforming growth factor beta (TGF-beta) superfamily pathways." [PRO:CNA]
comment: Category=family.
xref: PIRSF:PIRSF037286
is_a: PR:000000001 ! protein