[Term]
id: PR:000000034
name: bone morphogenetic protein
def: "A TGF-beta-like cystine-knot cytokine that is related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors." [PIRSF:PIRSF037272]
comment: Category=family.
xref: PIRSF:PIRSF037272
is_a: PR:000000008 ! TGF-beta-like cystine-knot cytokine