[Term]
id: PR:000000036
name: BMP receptor type-1B
def: "A TGF-beta superfamily receptor type-1 that is a translation product of the human BMPR1B gene or a 1:1 ortholog thereof. Bone morphogenetic protein (BMP) signals are transmitted by type 2 and type 1 serine/threonine kinase receptors. Type 2 receptors phosphorylate and activate type 1 receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMPS/OP-1." [PRO:CNA]
comment: Category=gene.
synonym: "BMPR1B" EXACT PRO-short-label [PRO:DNx]
synonym: "activin receptor-like kinase 6" EXACT []
synonym: "ALK-6" EXACT []
synonym: "BMP type-1B receptor" EXACT []
synonym: "BMPR-1B" EXACT []
synonym: "CDw293" EXACT []
synonym: "serine/threonine-protein kinase receptor R6" EXACT []
synonym: "SKR6" EXACT []
synonym: "Acvrlk6" RELATED Gene-based []
xref: IUPHARobj:1789
property_value: has_archetype PR:O00238
is_a: PR:000000006 ! TGF-beta superfamily receptor type-1