[Term]
id: PR:000000122
name: Rho-related small GTPase
def: "A small GTPase with a short insert (approximately 13 residues) coincident with loop 8 of Ras. This insert region forms a highly charged helix without dramatic disturbance of the global structure shared with other small GTPases. Rho-related small GTPases act as key transducers of extracellular signals to regulate the actin cytoskeleton, cell cycle progression and gene expression." [PMID:11463812]
comment: Category=family.
synonym: "fam:RHO" EXACT PRO-short-label [PRO:DAN]
xref: PIRSF:PIRSF037169
is_a: PR:000000028 ! small GTPase