[Term]
id: PR:000000538
name: c-myc protein isoform 1 phosphorylated 2
def: "A c-myc protein isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser and Thr residues within the L[LY]PTLTPPLS sequence of the Myc box I within the amino-terminal regulatory domain, by ERK and GSK3, respectively. Example: UniProtKB:P01106-1, Thr-58, MOD:00047|Ser-62, MOD:00046." [PMID:14563837, PMID:8386367]
comment: Category=modification. Note: This form is not stable and is degraded through the proteosome pathway.
synonym: "MYC/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000422 ! c-myc protein isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine