[Term]
id: PR:000000563
name: Rho-associated protein kinase 1 isoform 1 cleaved 1
def: "A Rho-associated protein kinase 1 isoform 1 that has been processed by caspase-3 downstream the sequence motif DETD, removing the inhibitory C-terminus." [PMID:11283607, PMID:16983089]
comment: Category=modification. Note: This form has been found significantly elevated in mouse myopathy model and human heart failure patients.
synonym: "ROCK1/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
synonym: "constitutively active ROCK-1" EXACT []
is_a: PR:000000307 ! Rho-associated protein kinase 1 isoform 1
relationship: output_of GO:0016485 ! protein processing