[Term]
id: PR:000000567
name: ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1
def: "A ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated form in which the phosphorylation occurs within the AGC-kinase C-terminal domain. Example: UniProtKB:P23443-1, Ser-441/Ser-447, MOD:00046|Thr-444, MOD:00047." [PMID:1922062]
comment: Category=modification. Note: AGC kinases are serine/threonine protein kinases. The phosphorylation sites serve as phosphorylation-regulated switches to control both intra- and inter-molecular interactions. Without these priming phosphorylations, the kinases are catalytically inactive.
synonym: "RPS6KB1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000463 ! ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine