[Term]
id: PR:000000568
name: ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1
def: "A ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated form in which the phosphorylation occurs within the AGC-kinase C-terminal domain. These sites serve as phosphorylation-regulated switches to control both intra- and inter-molecular interactions. Without these priming phosphorylations, the kinases are catalytically inactive." [PMID:1922062]
comment: Category=modification. Note: AGC kinases are serine/threonine protein kinases.
synonym: "RPS6KB1/iso:2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000464 ! ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine