[Term]
id: PR:000000657
name: smad3 isoform 1 acetylated and phosphorylated 1
def: "A smad3 isoform 1 acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated at a Lys residue within the MH1 domain by coactivators, such as CBP and EP300. Example: UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046." [PMID:17074756]
comment: Category=modification.
synonym: "SMAD3/iso:1/AcPhos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000577 ! smad3 isoform 1 acetylated and phosphorylated form
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: has_part MOD:00046 ! O-phospho-L-serine