[Term]
id: PR:000000979
name: voltage-gated potassium channel subunit KCNA7 isoform 1
def: "A voltage-gated potassium channel subunit KCNA7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q17ST2-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: This isoform contains an Hx20CxCC motif--resembling a metal coordination motif--in the N-terminal region. The N terminus appears to be a key component in the redox sensitivity of Kv1.7 channel inactivation. This form contributes to channels that inactivate fast and are sensitive to redox modulation.
synonym: "KCNA7/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "Kv1.7L" RELATED []
synonym: "Potassium voltage-gated channel subfamily A member 7 isoform 1" RELATED []
property_value: has_archetype PR:Q17ST2-1
is_a: PR:000000814 ! voltage-gated potassium channel subunit KCNA7