[Term]
id: PR:000001026
name: lymphocyte antigen 75
def: "A C-type lectin with multiple lectin domains that is a translation product of the mouse LY75 gene or a 1:1 ortholog thereof. It consists of 12 extracellular domains (an N-terminal cysteine-rich domain, a fibronectin type II domain and 10 C-type carbohydrate recognition domains), a transmembrane region and a small cytoplasmic C terminus containing a single Tyr residue, but no obvious kinase domain." [PMID:9862343]
comment: Category=gene. Requested by=CL. Note: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment.
synonym: "LY75" EXACT PRO-short-label [PRO:DNx]
synonym: "C-type lectin domain family 13 member B" EXACT []
synonym: "CD205" EXACT []
synonym: "DEC-205" EXACT []
synonym: "gp200-MR6" EXACT []
synonym: "ly-75" EXACT []
synonym: "CLEC13B" RELATED []
property_value: has_archetype PR:Q60767
is_a: PR:000001025 ! C-type lectin with multiple lectin domains