[Term]
id: PR:000001096
name: Toll-like receptor
def: "A protein that has a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582)." [PMID:11022119]
comment: Category=family.
synonym: "fam:TLR" EXACT PRO-short-label [PRO:DAN]
xref: PIRSF:PIRSF800008
is_a: PR:000000001 ! protein