[Term]
id: PR:000001353
name: granulocyte colony-stimulating factor receptor
def: "A protein that is a translation product of the human CSF3R gene or a 1:1 ortholog thereof. The active receptor is a homodimer which can bind G-CSF and transduce G-CSF-triggered growth signals into cells. Its extracellular domain contains a sequence of about 200 amino acids which can be found in various cytokine receptors. In addition, it contains an immunoglobulin-like domain and three fibronectin type III domains." [PRO:CNA, PMID:1723014]
comment: Category=gene.
synonym: "CSF3R" EXACT PRO-short-label [PRO:DNx]
synonym: "CD114" EXACT []
synonym: "G-CSF receptor" EXACT []
synonym: "G-CSF-R" EXACT []
synonym: "Csfgr" RELATED Gene-based []
synonym: "GCSFR" RELATED Gene-based []
xref: IUPHARobj:1719
property_value: has_archetype PR:Q99062
is_a: PR:000000001 ! protein