[Term] id: PR:000001423 name: histamine H2 receptor def: "A histamine receptor that is a translation product of the human HRH2 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates smooth muscle relaxation, gastric acid secretion, and other diverse effects." [PRO:WCB, PMID:9311023] comment: Category=gene. synonym: "HRH2" EXACT PRO-short-label [PRO:DNx] synonym: "gastric receptor I" EXACT [] synonym: "H2 histamine receptor" EXACT [] synonym: "H2R" EXACT [] synonym: "HH2R" EXACT [] xref: IUPHARobj:263 xref: PIRSF:PIRSF038634 property_value: has_archetype PR:P25021 is_a: PR:000049994 ! histamine receptor