[Term]
id: PR:000001550
name: proteinase-activated receptor
def: "A rhodopsin-like G-protein coupled receptor that is a translation product of the human F2R, or F2RL1 to F2RL3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds trypsin-related proteinases. The proteinase cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity." [PRO:WCB, PRO:XQ]
comment: Category=family.
synonym: "fam:PAR" EXACT PRO-short-label [PRO:DAN]
xref: IUPHARfam:59
xref: PIRSF:PIRSF037996
is_a: PR:000001094 ! rhodopsin-like G-protein coupled receptor