[Term]
id: PR:000001658
name: prostaglandin E2 receptor EP2 subtype
def: "A prostanoid receptor that is a translation product of the human PTGER2 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is expressed mediates various effects, including relaxation of vascular smooth muscles, nonacid secretion from epithelial cells, inhibition of mediator release from mast cells and basophils, and activation of sensory afferent nerves." [PRO:WCB, PMID:7938166]
comment: Category=gene.
synonym: "PTGER2" EXACT PRO-short-label [PRO:DNx]
synonym: "PGE receptor EP2 subtype" EXACT []
synonym: "PGE2 receptor EP2 subtype" EXACT []
synonym: "prostaglandin E2 receptor EP2" EXACT []
synonym: "prostanoid EP2 receptor" EXACT []
synonym: "Ptgerep2" RELATED Gene-based []
xref: IUPHARobj:341
property_value: has_archetype PR:P43116
is_a: PR:000001549 ! prostanoid receptor