[Term]
id: PR:000001662
name: proteinase-activated receptor 2
def: "A proteinase-activated receptor that is a translation product of the human F2RL1 gene or a 1:1 ortholog thereof. It is activated by trypsin and trypsin-like proteinases, which cleave the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity." [PRO:WCB, PMID:7556175]
comment: Category=gene.
synonym: "F2RL1" EXACT PRO-short-label [PRO:DNx]
synonym: "coagulation factor II receptor-like 1" EXACT []
synonym: "G-protein coupled receptor 11" EXACT []
synonym: "PAR-2" EXACT []
synonym: "thrombin receptor-like 1" EXACT []
synonym: "Gpcr11" RELATED Gene-based []
synonym: "GPR11" RELATED Gene-based []
synonym: "PAR2" RELATED Gene-based []
xref: IUPHARobj:348
property_value: has_archetype PR:P55085
is_a: PR:000001550 ! proteinase-activated receptor