[Term]
id: PR:000001706
name: sphingosine 1-phosphate receptor 1
def: "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR1 gene or a 1:1 ortholog thereof. The receptor is specifically expressed in endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin." [PRO:WCB, UniProtKB:P21453]
comment: Category=gene.
synonym: "S1PR1" EXACT PRO-short-label [PRO:DNx]
synonym: "CD363" EXACT [ImmPort:DSD]
synonym: "endothelial differentiation G-protein coupled receptor 1" EXACT []
synonym: "lysophospholipid receptor B1" EXACT []
synonym: "S1P receptor 1" EXACT []
synonym: "S1P receptor Edg-1" EXACT []
synonym: "S1P1" EXACT []
synonym: "sphingosine 1-phosphate receptor Edg-1" EXACT []
synonym: "CHEDG1" RELATED Gene-based []
synonym: "EDG1" RELATED Gene-based []
synonym: "Lpb1" RELATED Gene-based []
xref: IUPHARobj:275
property_value: has_archetype PR:P21453
is_a: PR:000001673 ! lysophospholipid (S1P) receptor