[Term] id: PR:000001923 name: receptor-type tyrosine-protein kinase Tie def: "A protein with core architecture consisting of an extracellular region containing an Ig-like domain (Pfam:PF00047 or Pfam:PF10430), followed by 3 EGF-like domains (Pfam:PF07947 or Pfam:PF00053), another Ig-like domain, and 3 Fibronectin type III domains (Pfam:PF00041), and a cytoplasmic region containing the Protein tyrosine kinase domain (Pfam:PF07714)." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF000630 is_a: PR:000000001 ! protein