[Term]
id: PR:000001974
name: voltage-gated calcium channel subunit alpha
def: "A voltage-gated calcium channel protein that has a core architecture consisting of four similar domains (I-VI), each containing six transmembrane helices (S1-S6), with a pore loop between S5 and S6. The S4 segments contain positively charged amino acids at every third position and serve as voltage sensors. Four Ion transport protein domains (Pfam:PF00520) are present. These may be followed by an IQ calmodulin-binding motif (Pfam:PF00612)." [PRO:WCB]
comment: Category=family.
xref: PIRSF:PIRSF005657
is_a: PR:000044658 ! voltage-gated calcium channel protein