[Term]
id: PR:000003509
name: histone acetyltransferase KAT6B/CREB-binding protein (human)
def: "A chimeric protein that consists of part of the human KAT6B gene at the N terminus and part of the human CREBBP gene at the C-terminus. It includes the zinc fingers, 2 nuclear localization signals, the histone acetyltransferase (HAT) domain, a portion of the acidic domain of KAT6B and the zinc fingers, KIX domain, bromodomain and CREB-binding domain from CREBBP. This form is observed in some cases of acute myelogenous leukemia where chromosomal translocation occurs." [PMID:11157802]
comment: Category=organism-gene.
synonym: "hKAT6B/CBP(chimera)" EXACT PRO-short-label [PRO:DAN]
synonym: "histone acetyltransferase MYST4/CREB-binding protein (human)" EXACT [PRO:DAN]
synonym: "MORF/CBP (human)" EXACT [PRO:DAN]
synonym: "MYST4/CBP chimera (human)" EXACT [PRO:DAN]
is_a: PR:000003507 ! chimeric protein
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens