[Term]
id: PR:000026145
name: serine palmitoyltransferase complex core 2 (human)
def: "A protein-containing complex that is heterodimeric consisting of one subunit of serine palmitoyltransferase 1 and serine palmitoyltransferase 3. These components are encoded in the genome of human. The biological unit of SPT complex may consist of multiple copies of the core 1 and/or core 2 in combination with additional subunits." [PRO:CNA, PMID:17331073, PMID:19648650]
comment: Category=organism-complex. This entity is disposed to have the enzymatic activity described by EC:2.3.1.50.
synonym: "3-oxosphinganine synthetase, acyl-CoA:serine C-2 acyltransferase decarboxylating (human)" BROAD [PRO:DNx]
synonym: "SPT (human)" BROAD [PRO:DNx]
is_a: GO:0032991 ! protein-containing complex
relationship: has_component PR:O15269 {cardinality="1"} ! serine palmitoyltransferase 1 (human)
relationship: has_component PR:Q9NUV7 {cardinality="1"} ! serine palmitoyltransferase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens