[Term]
id: PR:000026200
name: focal adhesion kinase 1, initiator methionine removed phosphorylated 2
def: "A focal adhesion kinase 1, initiator methionine removed form that has been phosphorylated on residues at positions equivalent to Tyr-407, Tyr-576, Tyr-577, Tyr-861, and Tyr-925 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-354128]
comment: Category=modification. Note: Tyr-397 phosphorylation is achieved via autocatalysis while the remainder are phosphorylated by SRC. Kinase=("PTK2"; PR:000018781; Tyr-397). Kinase=("SRC"; PR:000027238; Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925).
synonym: "PTK2/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000018781 ! focal adhesion kinase 1, initiator methionine removed form
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine