[Term]
id: PR:000026209
name: fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1
def: "A fibroblast growth factor receptor substrate 2, initiator methionine removed form that has been phosphorylated by activated TrkA. FRS2 is an adapter protein that links NGF receptors to downstream signaling pathways. It is involved in the activation of MAP kinases. Example: UniProtKB:Q8WU20-1, Tyr-196/Tyr-306/Tyr-349/Tyr-392/Tyr-436/Tyr-471, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-170959, Reactome:R-HSA-190062]
comment: Category=modification.
synonym: "FRS2/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "Phospho-Frs2" RELATED []
is_a: PR:000019931 ! fibroblast growth factor receptor substrate 2, initiator methionine removed form
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine