[Term]
id: PR:000027187
name: IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse)
def: "An IRAK4:MYD88:TIRAP:activated TLR4 complex in mouse that is composed of activated TLR4 receptor, the long isoform of MyD88, Tirap/Mal, and IRAK4." [TLR:AMM, PMID:12538665]
comment: Category=organism-complex. Requested by=TLR.
synonym: "IRAK4:MyD88:Mal:activated TLR4 (mouse)" EXACT []
is_a: PR:000027182 ! IRAK4:MYD88:TIRAP:activated TLR4 complex
relationship: has_component CHEBI:16412 ! lipopolysaccharide
relationship: has_component PR:000027172 ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:000027181 ! interleukin-1 receptor-associated kinase 4 unmodified form (mouse)
relationship: has_component PR:000027171 ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:Q99JY1 ! Toll/interleukin-1 receptor domain-containing adapter protein (mouse)
relationship: has_component PR:P22366-1 ! myeloid differentiation primary response protein MyD88 isoform 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus