[Term]
id: PR:000027431
name: microtubule-associated protein tau phosphorylated 3
def: "A microtubule-associated protein tau phosphorylated form in which the phosphorylation occurs at the first tyrosine and first Ser in the motif YSSPGS. Example: UniProtKB:P10636-1, Tyr-514, MOD:00048|Ser-515, MOD:00046." [PRO:CG]
comment: Category=modification. Requested by=Alzforum. The canonical sequence for UniProtKB human tau is based on isoform PNS-tau, while much of the literature uses numbering based on isoform hTau40.
synonym: "MAPT/Phos:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000026989 ! microtubule-associated protein tau phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine