[Term]
id: PR:000027462
name: apoptosis regulator Bcl-2 isoform 1 phosphorylated 3
def: "An apoptosis regulator Bcl-2 isoform 1 phosphorylated form in which the phosphorylation occurs at the three major phosphorylation sites (Thr and two conserved Ser residues) within the motif TSPLx(7-10)GPxLS, which is part of the non-structural N-terminal loop between BH4 and BH3 regions. Example: UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-70/Ser-87, MOD:00046." [PRO:PD, PMID:18570871, PMID:19029119]
comment: Category=modification.
synonym: "BCL2/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003088 ! apoptosis regulator Bcl-2 isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine