[Term]
id: PR:000027765
name: cellular tumor antigen p53 isoform 1 dimethylated 1
def: "A cellular tumor antigen p53 isoform 1 that has been dimethylated on a Lys residue present in the [KR]Kx(2)[LF]K[TR] sequence within the C-terminal regulatory region. This modification may promote p53 stability in response to DNA damage signals. Example: UniProtKB:P04637-1, Lys-382, MOD:00084." [PRO:PD, PMID:18840612]
comment: Category=modification.
synonym: "TP53/iso:1/Me2:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003036 ! cellular tumor antigen p53 isoform 1
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine