[Term]
id: PR:000028750
name: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1 (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1 in human. Acetylation within the PDZ domain alters PTEN interaction with PDZ domain-containing proteins, and thus may modulate PTEN function. UniProtKB:P60484-1, Lys-402, MOD:00064." [PRO:PD, PMID:18757404]
comment: Category=organism-modification. Acetylase=("CREBBP"; PR:Q92793; Lys-402).
synonym: "hPTEN/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P60484-1, Lys-402, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: PR:000028749 ! phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine