[Term]
id: PR:000028988
name: sterol regulatory element-binding protein
def: "A protein that is a transmembrane protein where the N- and C-termini are both cytosolic, and the N terminus contains a basic helix-loop-helix domain (Pfam:PF00010) and functions as a transcription factor when cleaved off." [PMID:17303406]
comment: Category=family.
synonym: "sterol regulatory element-binding transcription factor" EXACT []
synonym: "SRE" RELATED []
synonym: "SREBF" RELATED []
synonym: "SREBP" RELATED []
synonym: "bHLHd1" BROAD [PRO:DNx]
synonym: "class D basic helix-loop-helix protein 1" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein