[Term]
id: PR:000030192
name: catenin beta-1 isoform 1 phosphorylated 1 (human)
def: "A catenin beta-1 isoform 1 phosphorylated 1 in human. Phosphorylation at Ser-663 is found in many human colon cancer cells and tissues, which display a high PAK1 activity, or in response to Wnt3a stimulation. Ser-675 can be phosphorylated by either PAK1 or PKA. UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046." [PRO:IC, PMID:22369945]
comment: Category=organism-modification. Kinase=("PAK1"; PR:000035776; Ser-663/Ser-675). Kinase=("PKA"; PR:000029188; Ser-675).
synonym: "hCTNNB1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: PR:000030191 ! catenin beta-1 isoform 1 phosphorylated 1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_part MOD:00046 ! O-phospho-L-serine