[Term]
id: PR:000035427
name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that has been phosphorylated at one or more CDK1 and PLK1 consensus sites. The phosphorylation at CDK1 site(s) is necessary for the phosphorylation at the PLK1 site(s) to occur. Example: UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047)." [PRO:KER, PMID:10593653, PMID:11030144, PMID:11792804, PMID:17276342, PMID:17376779, PMID:17785528, PMID:18440313]
comment: Category=modification.
synonym: "BUB1B/Phos:CDK1+PLK1" EXACT PRO-short-label [PRO:DAN]
synonym: "BUBR1 phosphorylated" RELATED []
is_a: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00696 ! phosphorylated residue