[Term]
id: PR:000035499
name: spindle assembly checkpoint component MAD3
def: "A protein that is a translation product of the yeast MAD3 gene or a 1:1 ortholog thereof. MAD3 is related to BUB1 and BUB1B, all of which contain the Mad3/BUB1 homology region 1 (Pfam:PF00831), but MAD3 lacks the C-terminal Protein kinase domain (Pfam:PF00069)." [PRO:KER, PMID:15970700, PMID:22698286]
comment: Category=gene.
synonym: "MAD3" EXACT PRO-short-label [PRO:DNx]
synonym: "Mitotic MAD3 protein" BROAD [PRO:DNx]
property_value: has_archetype PR:P47074
is_a: PR:000000001 ! protein