[Term]
id: PR:000036052
name: IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex
def: "A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2 (TRAM), Ticam1 (TRIF), the death receptor RIPK1 (RIP1) cross-linked to K63-linked polyubiquitin, and the IKK complex (consisting of IKKA, IKKB and NEMO)." [PMID:15064760, PMID:15814722, PMID:16115877, Reactome:R-HSA-937030]
comment: Category=complex. Requested by=TLR.
synonym: "activated TLR4:TRIF:K63-pUb-RIP1:IKKcomplex" EXACT [Reactome:R-HSA-937030]
is_a: GO:0032991 ! protein-containing complex