[Term]
id: PR:000036076
name: activated TLR4 complex
def: "A protein-containing complex that contains TLR4, LPS and MD2(LY96)." [PRO:DAN, TLR:AMM, PMID:19252480, Reactome:R-HSA-166041]
comment: Category=complex. Requested by=TLR. Based on the crystal structure, known points of disulfide bonding, and other information, it is likely that the protein components correspond to PR:000003299 and PR:000025492. [PRO:DAN]
synonym: "TLR4actv" EXACT PRO-short-label [PRO:DAN]
synonym: "LY96:LPS:TLR4 complex" EXACT []
synonym: "MD2:LPS:TLR4 complex" EXACT []
synonym: "TLR4MD2LPS complex" EXACT []
is_a: GO:0043235 ! receptor complex
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: has_component PR:000001155 {cardinality="2"} ! Toll-like receptor 4
relationship: has_component PR:000003296 {cardinality="2"} ! lymphocyte antigen 96