[Term]
id: PR:000036838
name: NS12345
def: "A dengue virus genome polyprotein proteolytic cleavage product that is derived from dengue virus genome polyprotein, N-glycosylated form and that contains the entire non-structural region of the dengue virus genome polyprotein only and is responsible for directing viral genomic RNA replication, including synthesizing negative- and positive-strand RNAs and forming the viral RNA cap structure. It consists of NS1, NS2A, NS3, NS4A, 2K, NS4B, and NS5." [PRO:ES, PMID:1433530, PMID:22022449]
comment: Category=modification. Requested by=IDODEN.
synonym: "DenV-NS12345" EXACT PRO-short-label [PRO:DAN]
synonym: "Non-structural proteins" EXACT []
synonym: "Nonstructural proteins" EXACT []
synonym: "NS1-NS2A-NS2B-NS3-NS4A-NS4B-NS5" EXACT []
intersection_of: PR:000036818 ! dengue virus genome polyprotein proteolytic cleavage product
intersection_of: derives_from PR:000036817 ! dengue virus genome polyprotein, N-glycosylated form
intersection_of: has_part PR:000036831 ! 2K
intersection_of: has_part PR:000036824 ! NS1
intersection_of: has_part PR:000036825 ! NS2A
intersection_of: has_part PR:000036827 ! NS2B
intersection_of: has_part PR:000036828 ! NS3
intersection_of: has_part PR:000036830 ! NS4A
intersection_of: has_part PR:000036833 ! NS4B
intersection_of: has_part PR:000036835 ! NS5
intersection_of: lacks_part PR:000036836 ! C-prM
intersection_of: lacks_part PR:000036822 ! E protein