[Term]
id: PR:000037436
name: formin-1 isoform 5 phosphoserine (+/- phosphothreonine) form (mouse)
def: "A formin-1 isoform 5 (mouse) that has been phosphorylated on some Ser and possibly some Thr residues, but not on Tyr residues. UniProtKB:Q05860-5, (MOD:00046 and/or MOD:00047)." [PRO:KRC, PMID:14647292, PMID:8516300]
comment: Category=organism-modification. Note: In PMID:8516300, primary wild-type fibroblast cell lines were labeled with 32P, followed by immunoprecipitation with anti-formin peptide antisera and immunoprecipitated isoform IV was phospholabeled (Fig 3A). TLC phosphoamino acid analysis of formin IV transiently overexpressed in COS cells and immunoprecipitated demonstrated phosphorylation of serine and possibly threonine but no detectable labeling of tyrosine (Fig. 3C).
synonym: "mFMN1/iso:5/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "formin-1 (IV) phosphorylated 1" EXACT []
synonym: "formin-1 IV phosphorylated 1" EXACT []
synonym: "UniProtKB:Q05860-5, (MOD:00046 and/or MOD:00047)" EXACT PRO-proteoform-std [PRO:DAN]
is_a: PR:Q05860-5 ! formin-1 isoform 5 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus