[Term]
id: PR:000037467
name: LPS:secreted CD14 complex (mouse)
def: "An LPS:secreted CD14 complex whose components are encoded in the genome of mouse." [PMID:10601848, PMID:18606699]
comment: Category=organism-complex. Requested by=TLR. Note: PMID:10601848 shows evidence for complex in Figure 1, and indicates in the discussion that it uses the high M(r) form of sCD14. However, the authors show that the specific form of sCD14 found has the same M(r) as the mCD14, which is a hallmark of the shorter form. For this reason we consider the actual form used to be unclear. In PMID:18606699, evidence is indirect from response of endothelial epithelium to LPS with sCD14 depleted mouse plasma compared to normal.
synonym: "m-LPS:sCD14" EXACT PRO-short-label [PRO:DAN]
synonym: "sCD14/LPS complex (mouse)" EXACT []
is_a: PR:000029989 ! LPS:secreted CD14 complex
relationship: has_component CHEBI:16412 ! lipopolysaccharide
relationship: has_component PR:000036850 ! CD14 molecule cleaved and soluble form (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus