[Term]
id: PR:000037482
name: tyrosine-protein kinase BTK phosphorylated 1 (mouse)
def: "A tyrosine-protein kinase BTK (mouse) that is phosphorylated on two Tyr residues. Site 1 is a Tyr within the Src homology type 1 (SH1) domain and is transphosphorylated by a Src family tyrosine kinase. Site 2 is an autophosphorylation site within the Btk SH3 domain. UniProtKB:P35991, Tyr-223/Tyr-551, MOD:00048." [PMID:9326643]
comment: Category=organism-modification. Note: Activation of Btk correlates with an increase in the phosphorylation of two regulatory Btk tyrosine residues.
synonym: "mBTK/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35991, Tyr-223/Tyr-551, MOD:00048" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "active BTK" RELATED []
is_a: PR:P35991 ! tyrosine-protein kinase BTK (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus