[Term]
id: PR:000037552
name: microtubule-associated protein tau sequence variant R406W (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Trp residue at the position equivalent to Arg-406 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Arg-723 in PNS-Tau). Example: UniProtKB:P10636-8, Arg-406, CHEBI:29954." [PRO:DAN, Alzforum:KD, PMID:9382464]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010353 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:R406W" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636, Arg-723, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P10636-1, Arg-723, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P10636-8, Arg-406, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010353
xref: Alzforum_mut:mapt-r406w
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens