[Term]
id: PR:000044487
name: E3 ubiquitin-protein ligase HECTD1 ubiquitinated 1 (mouse)
def: "An E3 ubiquitin-protein ligase HECTD1 (mouse) that has been cross-linked to K63-linked polyubiquitin on one or more Lys residues by autocatalysis." [PRO:KRC, PMID:22431752]
comment: Category=organism-modification. UbLigase=("HECTD1"; PR:Q69ZR2). Evidence=(ECO:0000006, based on PMID:22431752). Note: PMID:22431752, Fig 2D shows the conjugation of K63-linked Ub chains onto Hectd1 is dependent on its ligase activity.
synonym: "mHECTD1/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "HECT domain-containing protein 1 ubiquitinated 1(mouse)" EXACT [UniProtKB:Q69ZR2]
synonym: "mHECTD1 K63-Ub" RELATED []
is_a: PR:Q69ZR2 ! E3 ubiquitin-protein ligase HECTD1 (mouse)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus