[Term]
id: PR:000044662
name: pH-gated ion channel protein
def: "A ligand-gated ion channel protein that has pH-gated monoatomic ion channel activity. A pH-gated ion channel opens when an extracellular proton has been bound by the channel complex, and enables the transmembrane transfer of a sodium ion." [PRO:DAN, PRO:XQ, GO:0160128]
comment: Category=family. Note: Acid-sensing ion channels operate as homo- or heterotrimers. [PRO:DAN, IUPHARfam:118]
synonym: "fam:ASIC_chan" EXACT PRO-short-label [PRO:DAN]
synonym: "acid-sensing ion channel protein" EXACT [PRO:DAN, GO:0044736]
synonym: "ASIC protein" EXACT [PRO:XQ]
synonym: "proton-gated ion channel protein" EXACT [PRO:DAN]
xref: IUPHARfam:118
intersection_of: PR:000044671 ! ligand-gated ion channel protein
intersection_of: capable_of GO:0160128 ! pH-gated monoatomic ion channel activity