[Term]
id: PR:000045022
name: histone H2AX, initiator methionine removed phosphorylated 2 (human)
def: "A histone H2AX (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-140 of the amino acid sequence represented by UniProtKB:P16104. UniProtKB:P16104, 2-143, Ser-140, MOD:00046." [PRO:DAN, PRO:JPB, PRO:JR, PMID:10734083, PMID:10959836, PMID:12660252, PMID:18370922, HIstome_var_Hs:Histone_H2A.x]
comment: Category=organism-modification.
synonym: "hH2AFX/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16104, 2-143, Ser-140, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "H2A.x:H2AS139ph" BROAD [HIstome_ptm_Hs:H2AS139ph]
xref: Reactome:R-HSA-75170 "PR:000045022 located_in GO:0005654"
is_a: PR:P16104 ! histone H2AX (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens