[Term]
id: PR:000045275
name: histone H3.3, initiator methionine removed trimethylated 1 (human)
def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-5, MOD:00083." [PRO:DAN, PRO:JPB, PRO:JR, PMID:12453418, PMID:16307923, PMID:16510874, PMID:16630819, PMID:16731913, PMID:17478518, PMID:18033247, PMID:18850007, PMID:20035052, PMID:21060806, PMID:21922516, HIstome_var_Hs:Histone_H3.3]
comment: Category=organism-modification.
synonym: "hH3.3/InitMet-/Me3:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P84243, 2-136, Lys-5, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "H3.3:H3K4me3" BROAD [HIstome_ptm_Hs:H3K4me3]
xref: Reactome:R-HSA-1214216 "PR:000045275 located_in GO:0005654"
xref: TDR:12549
is_a: PR:P84243 ! histone H3.3 (human)
relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens