[Term]
id: PR:000045291
name: histone H3.3, initiator methionine removed trimethylated 2 (human)
def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-28, MOD:00083." [PRO:DAN, PRO:JPB, PRO:JR, PMID:12351676, PMID:12649488, PMID:16630819, PMID:17200670, PMID:17314394, PMID:18318442, PMID:18628788, PMID:18632628, PMID:18716661, PMID:19340297, PMID:19557159, PMID:19887624, PMID:21115743, PMID:21228036, PMID:21242977, PMID:21512140, HIstome_var_Hs:Histone_H3.3]
comment: Category=organism-modification.
synonym: "hH3.3/InitMet-/Me3:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P84243, 2-136, Lys-28, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "H3.3:H3K27me3" BROAD [HIstome_ptm_Hs:H3K27me3]
xref: Reactome:R-HSA-212282 "PR:000045291 located_in GO:0005654"
is_a: PR:P84243 ! histone H3.3 (human)
relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens