[Term]
id: PR:000045308
name: histone H3.3, initiator methionine removed dimethylated 6 (human)
def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-10, MOD:00084." [PRO:DAN, PRO:JPB, PRO:JR, PMID:12232854, PMID:15153943, PMID:16861263, PMID:17314394, PMID:17901401, PMID:18552846, PMID:18776137, PMID:18850007, PMID:19349354, PMID:19739128, HIstome_var_Hs:Histone_H3.3]
comment: Category=organism-modification.
synonym: "hH3.3/InitMet-/Me2:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P84243, 2-136, Lys-10, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "H3.3:H3K9me2" BROAD [HIstome_ptm_Hs:H3K9me2]
xref: Reactome:R-HSA-427324 "PR:000045308 located_in GO:0005654"
xref: TDR:5808
is_a: PR:P84243 ! histone H3.3 (human)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens